Mucous membrane pemphigoid mmp is an autoimmune blistering disorder that is characterized by subepithelial blisters. Pdf treatment strategies in mucous membrane pemphigoid. Mucous membrane pemphigoid mmp this form of the disease affects the eyes, mouth, and throat. Treatment strategies in mucous membrane pemphigoid article pdf available in therapeutics and clinical risk management 43.
Outcomes for mucous membrane pemphigoid depend on early. Other diseases that produce the latter pattern linear band on. Bullous pemphigoid bp this strain is limited to the skin. Mucous membrane pemphigoid is a rare, chronic, blistering and scarring disease that affects the oral and ocular mucosa. Blistering and scarring may occur in the eyes, mouth, esophagus, larynx, and on the vulva. Various basement membrane zone components have been identified as targets of autoantibodies in mmp and the disease is characterised by dermatologists based on these components. Mucous membrane pemphigoid is a heterogeneous subepithelial blistering disease that predominantly affects the mucous membranes, including the conjunctiva and occasionally the skin. Abstract lichen planus pemphigoides lpp is a rare autoimmune subepidermal blistering disease characterized by the coexistence of both lichen planus and bullous pemphigoid or mucous membrane pemph. Scarring can result in severe structural changes to the vulva that may mimic the.
Mucous membrane pemphigoid is a rare autoimmune blistering disease primarily affecting mucosal surfaces. Mucous membrane pemphigoid mmp is a rare autoimmune bullous disease of the mucous membranes, which can cause irreversible scarring and is discussed to be associated with cancer, if laminin332. Mucous membrane pemphigoid mmp is an autoimmune blistering disorder that is characterized by subepithelial bullae. Levine early diagnosis and aggressive local and systemic therapy are critical to longterm visual outcome in cases of. Mucous membrane pemphigoid mmp is a rare, chronic, autoimmune, subepithelial blistering and erosive disease that affects the mucosal surfaces of the mouth gi it seems to us that you have your javascript disabled on your browser.
Like other forms of pemphigoid, the disorder is characterized by the formation of autoantibodies against structural proteins of the dermalepidermal junction. Other moist surfaces of the body known as mucous membranes can. Other mucosal sites that might be affected include the nasopharnyx, larynx, genitalia, rectum, and esophagus. Mmp is an uncommon blistering conditionwhich most frequently affects the lining of the mouth and gums. Other names include cicatricial pemphigoid, oral pemphigoid and ocular pemphigoid.
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